Looking for Jardiance alternatives? Discover the top drugs similar to Jardiance for managing type 2 diabetes and heart failure, including benefits, safety, and brand comparisons

What Is Jardiance?

Jardiance (empagliflozin) is a leading SGLT2 inhibitor used to manage type 2 diabetes, heart failure, and reduce the risk of cardiovascular death in adults. It works by helping the kidneys eliminate excess glucose through urine, improving both blood sugar and heart function.

If Jardiance doesn’t suit your needs due to side effects, insurance issues, or cost, there are other SGLT2 inhibitors that provide similar therapeutic benefits.

Best Drugs Similar to Jardiance

1. Farxiga (dapagliflozin)

• Very similar mechanism and FDA-approved for heart failure, diabetes, and chronic kidney disease (CKD)

• Also lowers the risk of cardiovascular events

• Taken once daily like Jardiance

2. Invokana (canagliflozin)

• First SGLT2 inhibitor approved in the U.S.

• Offers benefits for both kidney protection and cardiovascular health

• Slightly different side effect profile

3. Steglatro (ertugliflozin)

• Newer on the market

• Lower-cost alternative with similar glucose-lowering effects

• Often prescribed in combination with metformin

4. Synjardy

• A combination of Jardiance and metformin

• Helps reduce pill count for patients who need dual therapy

• Same benefits as Jardiance, with added glycemic control

5. Xigduo XR

• Combines Farxiga + metformin in one extended-release pill

• Enhances both fasting and post-meal blood glucose control

• Useful for patients seeking simplified regimens

Factors to Consider When Switching

• Kidney and liver function

• Heart failure diagnosis or risk

• Medication cost or insurance formulary

• Tolerance for side effects like dehydration or UTIs

• Medication interactions and pill burden

Always consult your healthcare provider before transitioning to or from Jardiance or any SGLT2 medication.